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Enteral feeding tubes
To ensure that you are clearly informed about how this procedure will be carried out, we invite you to read this information carefully. Your doctor is available to provide you with any additional information you may require. What is enteral nutrition? Malnutrition is a condition in which the body no longer functions properly because it is not receiving sufficient essential nutrients (carbohydrates, fats and proteins). In some situations, it becomes necessary to provide enteral nutrition: you then receive liquid food directly into the stomach or the first part of the small intestine (the jejunum), via a thin, flexible tube.  What type of tube will be used? The choice of tube depends on your disease and the anticipated duration of enteral nutrition.In most cases, a tube inserted through the nose—called a nasogastric or nasojejunal tube—is sufficient to improve your nutritional status. When enteral nutrition is required over the long term, the tube is inserted directly into the stomach (gastrostomy) or the small intestine (jejunostomy) endoscopically at the Digestive Endoscopy Clinic. How to prepare for gastrostomy placement? The gastrostomy is performed during a gastroscopy. To arrange for the tube to be placed, you will be seen by the clinical nutrition nurse or the gastroenterologist to prepare for your procedure. To prepare for your procedure: Inform your doctor about your medical history and all the medicines you take, particularly those that affect blood clotting: aspirin, Plavix, Sintrom, Xarelto, Eliquis, Pradaxa, Lixiana, Innohep, Fraxiparine (the list is not exhaustive).Inform your doctor of any known allergies.Fast for at least 6 hours before the examination: do not eat, drink or smoke.Depending on your situation, the examination will be performed under light sedation or general anaesthesia.  How is a gastrostomy placed? The procedure is performed by two gastroenterologists and generally takes between 15 and 30 minutes:The first doctor inserts an endoscope (a thin, flexible camera) through the mouth into the stomach.The second doctor identifies the best site on the abdominal wall from the outside, using the light from the endoscope.A small incision of a few millimetres is made in the skin after local anaesthesia.The tube is then passed from the inside outwards and secured in place, passing directly through the abdominal wall into the stomach (a technique commonly known as “pull gastrostomy”). What happens during the period after the gastrostomy is placed? After the procedure, you will remain in hospital for at least 2 days to ensure that enteral nutrition through the gastrostomy is well tolerated.The most frequent complications are pain around the tube opening, which is generally temporary. More rarely, bleeding or perforation may occur; these are detected promptly by means of an abdominal CT scan.Before you are discharged, the dietitian and theclinical nutrition nurse will explain the type and quantity of enteral nutrition suited to your situation, as well as how to use the tube at home. If necessary, home nursing care will be arranged before your discharge. How is follow-up carried out? Once the tube is in place, regular follow-up is essential to ensure your care proceeds smoothly:Regular consultations with the gastroenterologist and the clinical nutrition nurseDietary assessments to adapt your nutritional intake to changes in your conditionBlood tests to monitor your nutritional parametersFor young patients: the transition to adulthoodIf you have been followed in paediatrics until now, the transition to an adult service is prepared gradually from the age of 16:Your paediatrician will contact the adult team and provide them with all the information concerning your health and treatmentA first joint consultation — in the presence of your paediatrician and your new doctor responsible for your care — will be arranged, so that you do not feel alone during this stageIf necessary,, follow-up in both services (paediatric and adult) can be maintained for a maximum of 6 months in order to facilitate this transition in complete peace of mind. Contact You can make an appointment for a consultation (by email at ConsGastroMed [dot] erasme [at] hubruxelles [dot] be or by telephone on +32 (0)2 555.35.04, or contact the H.U.B Gastroenterology Department directly at SecMed [dot] GastroMed [dot] erasme [at] hubruxelles [dot] be (SecMed[dot]GastroMed[dot]erasme[at]hubruxelles[dot]be)You can also contact our clinical nutrition nurses, Asuncion Ballarin ( asuncion [dot] ballarin [at] hubruxelles [dot] be (asuncion[dot]ballarin[at]hubruxelles[dot]be)), Valerie Burion (val%C3%A9rie [dot] burion [at] hubruxelles [dot] be (valérie[dot]burion[at]hubruxelles[dot]be)), and, for the Jules Bordet Institute, Ingrid Amorison (ingrid [dot] amorison [at] hubruxelles [dot] be).  Discover the Pancreatology and Nutritional Support Clinic
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Discover Season 2 of the HÔP’Voices Podcast!
Visit our listening platforms to discover new patient testimonials, hospital professions, as well as the innovations shaping the medicine of tomorrow today! Behind every episode of this new season are three faces: Frédérique, Marine and Pauline. We meet you where you are to lend our microphone to those who bring the H.U.B to life. You have entrusted us with your stories… your emotions… your voices.This new season features moving testimonials, inspiring life journeys, innovations that are advancing medicine, and hospital professions that are sometimes still little known.Our aim? To take you to the heart of the H.U.B through the people who bring it to life every day.Join us now to discover the very first episode of season 2 of HÔP'VOICES!Listen on Spotify, Deezer and YouTube (@hopitaluniversitairebruxelles).  Image
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Pancreatology and Nutritional Support Clinic
The Pancreatology and Nutritional Support Clinic is a specialised medical unit dedicated to the diagnosis, treatment and follow-up of pancreatic diseases, as well as to the nutritional management of patients suffering from undernutrition, digestive disorders or requiring artificial nutrition. Contact the Clinic Are you a doctor and would like to obtain your patients’ medical results?Are you looking for information or do you need to deal with an administrative matter?Contact our medical secretariat by email at SecMed [dot] GastroMed [dot] erasme [at] hubruxelles [dot] be (SecMed[dot]GastroMed[dot]erasme[at]hubruxelles[dot]be)  Provide each patient with specialised care The Pancreatology and Nutritional Support Clinic is dedicated to providing each patient with specialised, personalised and multidisciplinary care, incorporating the latest medical and scientific advances in the fields of pancreatology and clinical nutrition. Image Image Image We are committed to: Diagnose and treat all pancreatic diseases, whether inflammatory (acute and chronic pancreatitis), autoimmune, hereditary or tumour-related, using state-of-the-art technical facilities (interventional endoscopy, advanced imaging and specialised surgery). Provide nutritional support for patients suffering from malnutrition, malabsorption or dependence on artificial nutrition (enteral or parenteral nutrition), in close collaboration with dietitians, clinical nurses and specialised pharmacists. Coordinate a multidisciplinary approach to ensure a rigorous diagnostic assessment and individualized therapeutic management, in line with current scientific recommendations. Promote clinical and fundamental research in the fields of pancreatology and nutrition, in order to continuously improve practices and provide our patients with access to the most innovative treatments. Train tomorrow’s healthcare professionals as part of our university mission, by sharing our expertise with students and doctors in training or visiting doctors who join us. Our range of care services •    Acute pancreatitis•    Chronic pancreatitis, including idiopathic and genetic forms•    Pancreatic cysts•    Autoimmune pancreatitis•    Malnutrition requiring artificial nutritional support (enteral or parenteral nutrition)•    Placement and management of enteral feeding tubes (by the Digestive Endoscopy Clinic)•    Short bowel syndrome•    Obscure gastrointestinal bleeding originating from the small intestine Our team Our multidisciplinary team, comprising specialist physicians, nurses and paramedical professionals, provides comprehensive and coordinated care for pancreatic diseases and nutritional disorders, in close collaboration with the general practitioner to ensure continuity of care. Prof. Marianna Arvanitakis, Director of the Pancreatology and Nutritional Support Clinic Gastroenterologist specialising in pancreatic diseases, interventional endoscopy and clinical nutrition. Professor Marianna Arvanitakis specialised in pancreatology and interventional endoscopy as part of Professor Jacques Devière’s team at Erasme Hospital. After obtaining a university diploma in Clinical Nutrition in 2005, she took over the medical coordination of the nutritional support service in 2018. The research conducted within the clinic focuses in particular on optimising the management of patients with severe acute pancreatitis and chronic pancreatitis, as well as on the management of patients suffering from short bowel syndrome. A member of several scientific societies, she is Secretary General of the European Society of Gastrointestinal Endoscopy (ESGE) for the 2025–2027 term and a clinical supervisor in gastroenterology for the Université libre de Bruxelles (ULB). Prof. Alia Hadefi Professor Hadefi is a gastroenterologist with expertise in clinical nutrition and metabolic liver diseases. She completed her doctoral thesis in 2024 on the interaction between the intestine and liver diseases, and undertook additional training in 2025 within the Department of Gastroenterology, Chronic Inflammatory Bowel Diseases (IBD) and Nutritional Support at Beaujon Hospital (Paris).Languages spoken: French, English, Arabic. Dr Michael Fernandez Y Viesca Dr Fernandez is a gastroenterologist with expertise in pancreatology, acquired after obtaining a university diploma in pancreatology in 2017 (Sorbonne). He is the coordinating physician for benign pancreatic diseases within the multidisciplinary pancreatology consultation and is currently preparing a doctoral thesis on severe acute pancreatitis.Languages spoken: French, English, Spanish. Wound care, stomatherapy, clinical nutrition A nursing team by your side to treat wounds, support people with a digestive stoma bag, and ensure appropriate nutrition.Clinical nutrition nurseErasmus HospitalAsuncion Ballarin, Stomatherapy nurse, clinical nutritionValérie Burion Jules Bordet InstituteIngrid Amorison   Meet our nursing team The departments with which the clinic collaborates Digestive surgery Lien vers Digestive surgery Digestive Oncology Lien vers Digestive Oncology Medical Imaging Lien vers Medical Imaging Interventional Radiology Lien vers Interventional Radiology Anatomical Pathology Centre Dietetics Lien vers Dietetics Hospital Pharmacy Lien vers Hospital Pharmacy Image Research and Innovation The Pancreatology and Nutritional Support Clinic is involved in various research projectsOptimisation of the management of patients with severe acute pancreatitis (Dr Fernandez Y Viesca), in collaboration with the Medical Imaging DepartmentChronic pancreatitis: Quality of life and Patient-Reported Outcomes (PROMs) (Dr Fernandez)Prevention of refeeding syndrome (RFS) using an application (Prof. Hadefi)Impact of endoscopic suturing gastroplasty (ENDOMINA) on liver diseases (steatohepatitis associated with liver dysfunction), in collaboration with the Centre of Pathological Anatomy (Prof. Hadefi)Study of new medications for short bowel syndrome (GLP-2 analogues) (Prof. Hadefi)Relationship between short bowel syndrome and liver diseases (Intestinal Failure-Associated Liver Disease (IFALD) (Prof. Hadefi) Resources and useful links [SCIENTIFIC ARTICLE] Pancreatic cysts and the risk of malignant transformation [SCIENTIFIC ARTICLE] Infected pancreatic necrosis and multidrug-resistant bacte… [SCIENTIFIC ARTICLE] Nutrition and diabetes [SCIENTIFIC ARTICLE] Endoscopic and percutaneous drainage for acute pancreatitis [SCIENTIFIC ARTICLE] European recommendations for exocrine pancreatic insuffici… [SCIENTIFIC ARTICLE] ESPEN European recommendations on clinical nutrition in ac… [SCIENTIFIC ARTICLE] Nutritional strategies for non-alcoholic fatty liver disea… [SCIENTIFIC ARTICLE] ASGE-ESGE recommendations on bariatric and metabolic endos… [ARTICLE] Feeding tube: a tool to take care of yourself when your body needs it
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MyHUB
MyHUB is the entire hospital just a click away! MyHUB: What is it? MyHUB is the application that gives you control of your relations with the Erasmus Hospital: Make an appointment Consult the diary of your scheduled appointments and hospitalisationsUpdate your contact details in our files: address, telephone number, GP, etc. Tell us where and when you want the options you indicate for your hospitalisations to apply (menu preferences, type of room, etc.) Read at leisure all the most important information for your hospital stayRegister your medication and receive a reminder of when you must take it (and easy communication of details to your doctor)For certain departments, make an appointment directly in the app.  MyHUB online Download the app and use Itsme to connect!Download MyHUB for AndroidDownload MyHUB for iOS Click for more informations Connecting to MyHUB without Itsme Nom | Naam Prénom | Voornaam Date de naissance | Geboorte datum Sexe | Geslacht Homme Femme Nationalité | Nationaliteit Numéro de téléphone portable | Telefoonnummer Adresse mail | E-mail adres NISS (uniquement pour personnes résidant en Belgique) | INSZ (alleen voor inwoners in België Adresse | Adres Rue et numéro | Straat en straatnummer Code postal | Postcode Commune | Gemeente Pays | Land
Health issues
Dysphagia
What is dysphagia? Eating, drinking, swallowing saliva… actions we perform every day without thinking about them. Yet, for some people, swallowing becomes difficult, painful or even dangerous. Dysphagia refers to swallowing disorders, that is, difficulties in properly passing food, drinks or saliva from the mouth to the stomach. It can occur at any age and have many causes. It may be due to a neurological cause (neurodegenerative disease, neuromuscular disease, cerebrovascular accident), a surgical cause (ENT, respiratory or cardiac surgery), prolonged intubation, ageing, certain medications, etc.  Dysphagia should not be trivialised: it can lead to weight loss, dehydration, or food or liquids entering the airways. Appropriate care can reduce these risks and preserve, as much as possible, the pleasure of eating and drinking.  When the problem is located in the mouth or throat This is referred to as oropharyngeal dysphagia. For example, the person may have difficulty preparing food in their mouth, initiating swallowing, or moving food and drinks towards the oesophagus. When the problem is located lower down This is referred to as oesophageal dysphagia. The person may feel that food is stuck or moves down with difficulty between the throat and the stomach. Dysphagia may be temporary or long-lasting. Key point: dysphagia is not a single disease. It is a symptom or disorder that can have various causes.  What are the symptoms? The signs are not always the same from one person to another. They may include: Coughing or choking during or after eating or drinking;Regularly needing to clear one’s throat during meals;Having a “wet” or hoarse voice after swallowing;Feeling as though food is stuck in the throat or chest;Having difficulty chewing;Keeping food in the mouth for a long time before swallowing it;Needing much more time to finish a meal;Food or drinks escaping through the mouth or sometimes the nose;Experiencing pain when swallowing;Avoiding certain foods or drinks because they are difficult to swallow;Drinking or eating less than before;Losing weight unintentionally;Having repeated episodes of respiratory infection or pneumonia.  Warning: it is sometimes possible to “aspirate” WITHOUT coughing Aspiration occurs when food, a drink or saliva enters the airways instead of passing into the oesophagus. This can sometimes happen without coughing or any obvious sign. This is known as silent aspiration. This is one of the reasons why a medical assessment may be necessary when several signs suggest dysphagia. How common is dysphagia in Belgium? To date, there is no sufficiently robust national Belgian figure to determine precisely how many people have dysphagia in Belgium. This difficulty is not specific to Belgium: international studies produce very different results depending on the age of the people studied, their state of health and, above all, how dysphagia is screened for or diagnosed. European recommendations generally estimate its prevalence at 10 to 20%, while emphasising that the level of evidence is low and that estimates vary according to the populations and definitions used.  Nevertheless, the available data show that dysphagia is particularly common in certain populations: Among older people living at home, studies report highly variable estimates; a recent meta-analysis estimates the pooled prevalence at approximately 18%.Among older people living in a care home, the pooled prevalence is approximately 47% in a meta-analysis.Among hospitalised older people, it may reach approximately 38%, depending on the method used to detect it.After a cerebrovascular accident, studies report particularly high rates, with estimates varying considerably according to the populations and assessment methods. One meta-analysis reports a prevalence of 55.4% among people who have had a cerebrovascular accident.  These figures cannot be directly extrapolated to the Belgian population as a whole. They mainly help explain why dysphagia is an important problem, particularly among older people or those with certain diseases.  Main sources for the figures UEG/ESNM, 2025 clinical guidelines: general prevalence estimated at 10–20%, with substantial variability according to the definitions and populations. Zhao et al., Prevalence and Methods for Assessment of Oropharyngeal Dysphagia in Older Adults, meta-analysis: 18.39% among older people living in the community, 46.98% in institutions and 37.98% in hospital. Dziewas et al./systematic review of care settings: 36.5% in hospital, 42.5% in rehabilitation and 50.2% in care homes. Wang et al., global meta-analysis: substantial variability according to the populations; 55.4% among patients who had suffered a cerebrovascular accident in the included studies.  What are the causes of dysphagia? Dysphagia can have many causes. It may notably be associated with: A cerebrovascular accident;Parkinson’s disease or other neurological diseases;Multiple sclerosis;Certain neuromuscular diseases;Dementia;Cancer of the mouth, throat or oesophagus;Surgery or radiotherapy in the head and neck region;Certain abnormalities of the oesophagus;Significant frailty or loss of muscle strength related to ageing.  The cause must therefore be investigated on a case-by-case basis.  How is dysphagia diagnosed? The first step generally consists of listening to the difficulties experienced by the person and taking a complete medical history: which foods cause problems? When does the coughing occur? Are liquids more difficult to swallow than solid foods? Has there been any weight loss or respiratory infections? Has there been a loss of appetite? Etc.  A healthcare professional can then carry out a thorough motor examination of the orofacial sphere, observe the person while they are eating and perform various swallowing tests. Depending on the symptoms and the suspected cause, additional examinations may be necessary. A specialist assessment A speech therapist specialising in swallowing disorders can assess how the person chews and swallows and identify the difficulties they are experiencing. Other specialists may be involved depending on the cause: general practitioner, ENT specialist, gastroenterologist, neurologist, dietitian, physiotherapist, nurse or other healthcare professionals. More in-depth examinations In certain situations, it is necessary to directly observe what happens during swallowing. Two examinations may in particular be used: Videofluoroscopy: an X-ray examination performed while the person swallows different consistencies;Fiberoptic Endoscopic Evaluation of Swallowing (FEES): a small flexible camera is used to observe the throat during swallowing.  These examinations provide a better understanding of where and why swallowing is problematic and help tailor the care provided.   How is dysphagia treated? There is no single treatment. Management depends on the cause, the type of dysphagia and each person’s abilities. The aim is twofold: to make swallowing as safe and effective as possible and to enable the person to continue eating and drinking in the best possible conditions. Swallowing rehabilitation The speech and language therapist may suggest exercises and techniques designed to improve certain movements or stages of swallowing. They may also teach different strategies: modifying the position of the head, adapting how a bite or sip is taken, slowing the pace of the meal, implementing safe postures, adapting the patient’s food textures, … Adapting food and drinks In some cases, it is necessary to temporarily or permanently modify the texture of food or the consistency of drinks. For example, certain foods can be chopped, blended or made easier to chew. Drinks can also be thickened when indicated. These adaptations must be personalised: a texture suitable for one person may not necessarily be suitable for another. The IDDSI (International Dysphagia Diet Standardisation Initiative) system enables the use of a common international classification to describe food textures and drink consistencies.  Treating the cause Whenever possible, treating the disease or problem causing the dysphagia is also essential. Preventing malnutrition and dehydration If the person is no longer able to eat or drink enough, a dietitian can adapt their food intake and suggest solutions to maintain a sufficient intake of energy and fluids. In some situations, tube feeding may be considered. This decision is made on a case-by-case basis with the person and the medical team. Management is therefore often multidisciplinary, involving several professionals working together.   Why should dysphagia be taken seriously? Unidentified or poorly managed dysphagia can have several consequences: Aspiration → respiratory infection Food or liquids may enter the airways and cause, in particular, aspiration pneumonia. Difficulty eating → malnutrition The person may gradually reduce the amount they eat or avoid certain foods. Difficulty drinking → dehydration Drinking may become difficult or tiring, which can lead to insufficient fluid intake. Difficult meals → loss of enjoyment Eating may become a source of worry, fatigue or social isolation.   When should you seek medical attention? Difficulty swallowing that recurs or persists should be discussed with a healthcare professional. It is particularly important to seek medical advice in the event of: Frequent coughing or choking during meals;A repeated sensation of food becoming stuck;Unexplained weight loss;A significant reduction in the amount of food or drink consumed;Repeated respiratory infections;A change in voice after swallowing;Difficulty that appears suddenly.  Sudden difficulty swallowing, particularly when accompanied by weakness on one side of the body, speech impairment or facial drooping, may be a sign of a cerebrovascular accident and constitutes a medical emergency.  Our specialists ENT Department: 02/555.37.75 ENT specialists in swallowing disorders:  Dr Nicolas ROPERDr Céline LAURENT  Speech therapists in the ENT Department:  Loriana SNELAlix LE JEMTEL   Discover our ENT department FAQ on dysphagia 1. Does dysphagia mean that I will inevitably choke? No. Dysphagia can take different forms, and its severity varies from one person to another. It may simply cause a sensation of blockage, make certain foods difficult to swallow, or lead to aspiration. 2. Is it normal to have more difficulty swallowing as you get older? Ageing can alter certain functions involved in swallowing. However, regular difficulty swallowing should not be considered a normal consequence of ageing. An assessment can help identify a cause and suggest solutions. 3. Why do I cough when I drink water? Coughing during or immediately after drinking may be a sign that the liquid is not passing properly into the oesophagus. This does not necessarily mean that you have dysphagia, but if it happens frequently, it is best to discuss it with a healthcare professional.   4. Is it possible to have dysphagia without coughing? Yes. Some aspiration episodes can be silent, without coughing or any obvious signs. 5. Can dysphagia go away? Yes, in certain situations. It may be temporary, particularly when it is related to an acute condition or certain treatments. In other cases, it may last longer and require rehabilitation or adaptations.  6. Can you still eat normally with dysphagia? It depends on the situation. Where possible, the aim of care is to enable the person to continue eating and drinking by mouth under appropriate safety conditions. 7. Why do drinks sometimes need to be thickened when you have dysphagia? Some people have greater difficulty controlling very thin liquids. In these situations, an adapted consistency can facilitate control of the drink during swallowing. This adaptation should be recommended following an appropriate assessment.  8. Who should you consult for dysphagia? Several professionals may be involved: a doctor, speech therapist, dietitian, nurse, physiotherapist, ENT specialist, gastroenterologist, neurologist, and so on. The professional involved depends in particular on the cause and the difficulties encountered. 9. Can dysphagia lead to weight loss? Yes. Difficulties swallowing can lead to eating less, avoiding certain foods or considerably prolonging mealtimes. This can contribute to malnutrition.   10. What should I do if I think I have dysphagia? Talk to your doctor or another healthcare professional. Do not wait until the difficulties become significant, especially if you regularly cough while eating or drinking, lose weight, or experience recurrent respiratory infections.
Dysphagia
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Pediatric spinal dysraphism and spinal deformities – Symposium
H.U.B Annual Symposium of Pediatric Neurosurgery and NeuropediatricsNovember 6, 2026 – Musée de la Médecine, Brussels Image A full-day multidisciplinary update on pediatric spinal dysraphism and spinal deformities Date & Location:November 6, 2026 – Musée de la MédecineRegistrationPROGRAM About the EventA multidisciplinary symposium dedicated to pediatric spinal dysraphism and spinal deformities, covering diagnosis and management from the prenatal period through childhood and long-term follow-up. The program will focus on spinal dysraphism, myelomeningocele and tethered cord syndrome, pediatric scoliosis and associated neuroaxis abnormalities, as well as disorders of the cervico-vertebral junction.Practical InformationDate: November 6, 2026Venue:  Musée de la Médecine – ULB-H.U.B., Hôpital ErasmeAddress: 808 Route de Lennik, 1070 BrusselsBy public transport: Brussels-Central or Brussels-Midi railway station, Metro 5 Erasme, STIB bus 74 or De Lijn bus R42. A paid covered car park with charging stations for electric vehicles is also available. ContactFor any inquiries, please contact:Info:Symposium [dot] Paeds [dot] Neurosurgery [at] hubruxelles [dot] be (Symposium[dot]Paeds[dot]Neurosurgery[at]hubruxelles[dot]be)  Service de Neurochirurgie - Hôpital Erasme H.U.BService de Neuropédiatrie - Erasme 
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6th Workshop of video-assisted technology in Thoracic Pathology
Organized: October 1st & 2nd 2026 at the Museum of Medicine (Erasmus Campus – Place Facultaire, Route de Lennik, 808, 1070 Brussels, Belgium). Please note: registration is free but mandatory, the event is organized on-site (no videoconferencing).  Discover the programme Find out more about the programme for the workshop, which takes place on 1 and 2 October 2026, and register using the online form. Programme Workshop of video-assisted technology in Thoracic Pathology Your personal data First name Last name Email Phone number Your profession Which institute are you working at? Your registration for the workshop : Video-assisted technology in Thoracic Pathology Jeudi 01/10/2026 - Thursday 10/01/2026 Vendredi 02/10/2026 - Friday 10/02/2026 Both days Your registration to the diner (Thursday evening -26/09/2024) Oui/Yes Non/no Please note: this is a paid dinner event. If you selected “Yes”, a fee of 50 euros will be charged. They support us This workshop is supported by:Belgian Respiratory Society (BeRS)Royal Belgian Society for Surgery (RBSS)Belgian Section of Thoracic Surgery (BeSTS) Our sponsors Contact Mélissa BourleauEmail : Melissa [dot] Bourleau [at] hubruxelles [dot] be (Melissa[dot]Bourleau[at]hubruxelles[dot]be)Phone number : +32 (0)2 555 53 49
Health issues
Primary immunodeficiencies
What is it? Primary immunodeficiencies are rare diseases, most often of genetic origin, in which part of the immune system does not function properly from birth. They affect both children and adults and may sometimes only become apparent later in life. They most commonly manifest as infections that recur frequently, last a long time or respond poorly to treatment; some are associated with autoimmune or inflammatory manifestations. Recognising these signs enables an appropriate diagnosis and management. In the event of unusual and recurrent infections, a specialist consultation, following referral by your general practitioner, is recommended. Assessment and diagnosis Our Immunodeficiency Treatment Unit brings together internist-immunologists, paediatricians, biologists, pulmonologists, gastroenterologists and infectious disease specialists around the patient. The process begins with an immunological assessment: measurement of antibodies (immunoglobulins IgG, IgA and IgM), evaluation of the response to vaccines, analysis of immune cells and, when useful, genetic testing. This assessment enables an accurate diagnosis and identification of the type of deficiency. Care is personalised: prevention and rapid treatment of infections, appropriate vaccinations and, for many antibody deficiencies, replacement therapy with immunoglobulins administered in hospital (intravenously) or at home (subcutaneously). Regular follow-up aims to detect and treat any complications (autoimmune, pulmonary or digestive) and to adapt treatment over time. This coordinated, multidisciplinary approach, from childhood through adulthood, improves quality of life and reduces the risk of complications. Advice On a daily basis, simple measures help limit infections: keeping vaccinations up to date, good hand hygiene, regular dental care and prompt treatment of infections. Most episodes can be managed on an outpatient basis. However, you should seek medical advice without delay, or even go to the Emergency Department on the advice of our available specialist doctors, in the event of a high and persistent fever, breathing difficulties, a sudden deterioration in your general condition, neck stiffness or signs of a severe infection. If in doubt, contact your healthcare team: it is better to make one call too many. Specific care pathway 1. First signs and referral — Recurrent, persistent or poorly responsive ENT, bronchial or pulmonary infections may suggest an immunodeficiency. The general practitioner or paediatrician then refers the patient to a specialist consultation.2. Assessment and diagnosis — A blood test measures antibodies (IgG, IgA and IgM) and the response to vaccines; analysis of immune cells and, sometimes, genetic testing complete the assessment. These tests confirm the diagnosis and determine its type, such as common variable immunodeficiency (CVID), the most common form in adults.3. Starting treatment — When an antibody deficiency is confirmed, replacement therapy with immunoglobulins is generally offered, either by intravenous infusion in hospital or subcutaneously at home. This is combined with prompt treatment of infections and appropriate vaccinations.4. Long-term follow-up — Regular consultations are used to monitor treatment effectiveness, adjust doses and detect any autoimmune, pulmonary or digestive complications. Follow-up is coordinated between the various specialists.5. Daily life and support — Therapeutic education, support from patient associations and, for children, planning the transition to the adult team help patients live as well as possible with the condition. Useful documents File trajet.pdf File 2026_medecine_interne_immunodeficiences_primaires_document_deficits_immunitaires_secondaires.pdf File 2026_medecine_interne_immunodeficiences_primaires_document_entites_frontieres.pdf File 2026_medecine_interne_immunodeficiences_primaires_document_deficits_immunitaires_combines.pdf File 2026_medecine_interne_immunodeficiences_primaires_document_deficits_immunitaires_combines_severes.pdf File 2026_medecine_interne_immunodeficiences_primaires_document_deficits_du_complement.pdf File 2026_medecine_interne_immunodeficiences_primaires_document_deficit_selectif_iga.pdf File 2026_medecine_interne_immunodeficiences_primaires_document_deficit_immunitaire_commun_variable.pdf File 2026_medecine_interne_immunodeficiences_primaires_document_deficit_en_anticorps_specifiques.pdf File 2026_medecine_interne_immunodeficiences_primaires_document_defauts_phagocytaires.pdf File 2026_medecine_interne_immunodeficiences_primaires_document_defauts_de_commutation_de_classe.pdf Transition to adulthood Many primary immunodeficiencies diagnosed in childhood require lifelong follow-up. To ensure a seamless transition, the move from paediatrics to adult medicine is prepared in advance, progressively and with support. The young patient meets the adult care team, gains a better understanding of their condition and treatment, and becomes more independent. Paediatricians and adult physicians share medical information so that the transition takes place smoothly, without any loss of information or interruption in care. Focus / Research Our team participates in international research on inborn errors of immunity. The work of Jean-Christophe Goffard, conducted in collaboration with major academic networks, has notably helped explain why some people develop severe forms of viral infection: it has demonstrated the role of autoantibodies directed against type I interferons—key molecules in antiviral defence—and of underlying immune deficiencies, for example in severe COVID-19. This research improves the diagnosis of immunodeficiencies and paves the way for more personalised care. Our Specialists Associated department
Primary immunodeficiencies
Health issues
Kleine–Levin syndrome
What is Kleine–Levin syndrome? Kleine-Levin syndrome (KLS) is a rare intermittent neuropsychiatric disorder (approximately 3 cases per million) that predominantly affects adolescents and young adults. It is characterised by symptomatic periods (“episodes” or “attacks”) lasting from one to several weeks, combining severe hypersomnia with cognitive, behavioural and psychiatric disorders.The episodes are separated by intercritical periods lasting from several weeks to several months, with a return to normal functioning.The course is variable, averaging around twenty episodes, and is often favourable: the disorder frequently disappears after the age of thirty.This favourable prognosis should not obscure the fact that some patients experience very distressing episodes (marked derealisation, sometimes severe behavioural disorders involving hyperphagia, hypersexuality, aggression, delusions or suicidal thoughts), prolonged episodes (lasting more than a month) or very frequent episodes, which affect their school, professional and family life.Furthermore, around one-third of young people develop, as a result of experiencing repeated episodes, persistent mild cognitive impairment between attacks, sleep disorders, anxiety or mood disorders. This is why it is important to make the diagnosis and, often, to treat these disorders. What are the symptoms? The classic presentation is that of an adolescent with no previous medical history who suddenly begins sleeping continuously (18 hours or more per day), stays in their room, lying down, confused, slowed down and apathetic (for example, no longer using their mobile phone), and experiences derealisation (the feeling of being in a dream). The episode lasts one or two weeks, after which the young person returns to completely normal. During the episode, varying degrees of severe anxiety, sadness, disinhibited behaviour (megaphagia, hypersexuality, rudeness) or delusional ideas may also occur. Since the first episode is often triggered by an infection or alcohol consumption, the doctor often suspects a viral illness or substance use, performs a brain MRI (normal), sometimes a lumbar puncture (normal), or recommends consulting a psychiatrist. A recurrence of the same symptoms several weeks or months later should suggest Kleine–Levin syndrome. How is the diagnosis carried out at Erasme? The diagnosis is mainly clinical: description, observation or video recording of the episodes by the family, and exclusion of other more common diagnoses. However, frequent abnormalities may be observed on the EEG during an episode and on functional brain imaging (PET scan), even during asymptomatic periods: hypometabolism of the posterior association cortex or hippocampus in 70% of cases. Predisposing factors include male sex and neonatal disorders. The cause is unknown, but some indirect evidence suggests that this is a recurrent inflammatory encephalopathy. What treatments are available? General management- Explanation of the disease: current knowledge and patient association.- Reduction of factors that trigger episodes: no alcohol or cannabis, sufficient and regular sleep, preventive measures, seasonal influenza and COVID-19 vaccination, and treatment of infections.- In the event of an episode: keep the patient at home, resting quietly in bed and often in the dark, under the supervision of the family, ensuring that they drink enough and eat a little. Urination is maintained. Never drive a vehicle during an episode (risk of an accident). Bring the patient home if an episode begins abroad.- Hospitalisation: only if there is a risk to the patient or others (severe delirium, suicidal thoughts, aggression).Drug treatmentThe treatment is selected and regularly reassessed by the neurologists responsible for the patient’s care. No treatment is also an option. However, on a case-by-case basis, depending on the degree of disability, particularly if the episodes are frequent (> 3/year), prolonged (> 1 month), or involve significant psychiatric symptoms, the following is recommended:Lithium at a therapeutic dose: beneficial in more than 83% of cases. It requires drinking plenty of fluids (water!), regular monitoring of lithium levels, TSH and creatinine levels, and an annual reassessment of its effectiveness. Please note that this disease is unrelated to bipolar disorder. Lithium is then gradually discontinued after 3 years without an episode.Treatment during an episode: intravenous methylprednisolone may be started at a dose of 1 gram/day for 3 consecutive days, with gastric protection. Who are the professionals involved in your care? NeurologistsCare pathway coordinator: Prof. Mélanie Strauss. Dr Faustine Lebout Experts in diagnosis, treatment and specialised follow-up.General practitionerFirst-line follow-up and coordination with the specialist.NeuropsychologistComprehensive neuropsychological assessment and coordinated support by Mr Hichem SlamaPsychoeducation. Support in coping with the impact of the disease, self-esteem and social life.Psychologist / child and adolescent psychiatristIn the event of anxiety or depressive symptoms, or difficulties adapting related to the disease. Useful links Orphanet (medical information, ORPHA code) Our specialists
Kleine–Levin syndrome